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Updated: May 21, 2026
07:32
Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles
Published on: August 28, 2015
Polymeric particulate technologies for oral drug delivery and targeting: a pathophysiological perspective
A Christy Hunter1, Jacqueline Elsom, Peter P Wibroe
1University of Manchester, Department of Pharmacy and Pharmaceutical Sciences, Manchester, UK. christy.hunter@manchester.ac.uk
Maturitas
|June 20, 2012
Summary
Polymeric nanoparticles and microparticles enhance oral drug delivery. This review details advanced nanocarrier systems and their behavior in the gastrointestinal tract.
Area of Science:
- Pharmaceutical Sciences
- Materials Science
- Biotechnology
Background:
- Oral drug delivery is the most common pharmaceutical administration route.
- Nanoparticles and microparticles are advanced systems for drug delivery.
- Polymeric materials are frequently used in these nanocarrier systems.
Purpose of the Study:
- To review cutting-edge nanocarrier technologies for oral drug delivery.
- To focus on the interaction and fate of polymeric nanocarriers in the gastrointestinal system.
Main Methods:
- Literature review of nanocarrier systems.
- Analysis of polymer interactions within the gastrointestinal environment.
Main Results:
- Overview of polymeric nanoparticles, solid lipid nanocarriers, self-nanoemulsifying drug delivery systems, and nanocrystals.
- Discussion of the gastrointestinal fate of these polymeric nanocarriers.
Conclusions:
- Polymeric nanocarriers represent a significant advancement in oral drug delivery.
- Understanding their gastrointestinal fate is crucial for optimizing drug targeting and bioavailability.
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