Related Experiment Videos
7-Substituted theophyllines. Part VI--N-[2-(4-chlorophenoxy)-1-phenyl-alkyl]-alkylamido derivatives
G Diamantini1, G Spadoni, A Salvatori
1Istituto di Chimica Farmaceutica, Università di Urbino, Italy.
Farmaco (Societa Chimica Italiana : 1989)
|June 1, 1990
Abstract:
The new amides are inhibitors of cholesterol biosynthesis in vitro as well as in vivo. These compounds are also inhibitors in vivo of triglyceride biosynthesis and of platelet aggregation. All tests showed activity (values expressed as percentage variation) much greater than clofibrate. Besides, all compounds have no effect on coagulation or diuresis and showed low acute toxicity.