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Determination of salicilic acid in saliva by high-performance liquid chromatography
V Cavrini1, R Gatti, A M Di Pietra
1Dipartimento di Scienze Farmaceutiche, Università, Bologna, Italy.
Farmaco (Societa Chimica Italiana : 1989)
|June 1, 1990
Abstract:
A sensitive reversed-phase HPLC method with fluorimetric detection was developed for the determination of salicilic acid in saliva samples. The method, involving a preliminary solid-phase extraction procedure, was found to be suitable for the determination of salivary salicilic acid concentrations following the administration of a single oral dose of some commercial acetylsalicilic acid formulations.