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Updated: May 21, 2026

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
Published on: November 10, 2023
[Minimally invasive surgery in the treatment of malignant pleuro-pericardial effusions]
1Spitalul Universitar de Urgenţă Militar Central Dr. Carol Davila, Bucureşti, Romania. adi_ciuche@yahoo.com
Introduction:
Malignant pleuro-pericardial effusions (MPPEs) are a common problem in the treatment of patients with cancer and may occur with any malignancy.
Methods:
Between 01.01.1998 -31.12.2008 we conducted a retrospective study. During this period of time 46 patients were diagnosed and treated for malignant pleuro-pericardial effusions in Clinic of Thoracic Surgery under Prof. Teodor Horvat coordination (from SUUMC).
Results:
In this study a total of 42 MPPEs have been approached through minimally invasive procedures (36 patients underwent thoracoscopic procedures and 6 patients were subjected to VATS). In our study, the pulmonary cancers were the most frequent primary cancers who caused MPPEs (22 cases). The thoracoscopic pleuro-pericardial window was the most frequent and efficient procedure used for pericardial drainage (34 cases). Effective control of the recurent malignant pleural and pericardial effusions was made most frequent through postoperative pleural bleomycin instillation (22 cases) and through thoracoscopic insufflation of talc in 14 cases.
Conclusions:
The minimally invasive thoracic surgery is a safe and efficient method for diagnosis and treatment of pleuro-pericardial effusions.
Insights
Minimally invasive thoracic surgery effectively treats malignant pleuro-pericardial effusions (MPPEs). This approach offers a safe and efficient solution for managing these common cancer-related fluid build-ups.
Area of Science:
- Thoracic Surgery
- Oncology
- Cardiology
Background:
- Malignant pleuro-pericardial effusions (MPPEs) are a frequent complication in cancer patients, irrespective of the primary malignancy.
- MPPEs pose a significant challenge in patient management and treatment.
- Understanding the efficacy of different treatment modalities for MPPEs is crucial.
Purpose of the Study:
- To evaluate the safety and efficacy of minimally invasive thoracic surgery for managing malignant pleuro-pericardial effusions.
- To identify the most common primary cancers leading to MPPEs.
- To assess the effectiveness of different procedures and postoperative treatments for controlling recurrent effusions.
Main Methods:
- A retrospective study was conducted between 1998 and 2008, analyzing 46 patients diagnosed with MPPEs.
- Minimally invasive procedures, including thoracoscopy and video-assisted thoracoscopic surgery (VATS), were employed.
- Data on primary cancer types, surgical procedures, and effusion control methods were collected.
Main Results:
- A total of 42 MPPEs were treated using minimally invasive techniques.
- Pulmonary cancers were the most frequent cause of MPPEs (22 cases).
- Thoracoscopic pleuro-pericardial window creation was the most common and effective pericardial drainage procedure (34 cases).
- Recurrent effusions were most effectively managed with postoperative bleomycin instillation (22 cases) and talc insufflation (14 cases).
Conclusions:
- Minimally invasive thoracic surgery provides a safe and efficient method for the diagnosis and treatment of malignant pleuro-pericardial effusions.
- Thoracoscopic procedures are a valuable tool in managing these complex effusions.
- Effective control of recurrent effusions can be achieved through targeted postoperative interventions.
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