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Updated: May 21, 2026
A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma
Published on: January 5, 2017
Cutaneous angiosarcoma of the scalp masquerading as a squamous cell carcinoma: case report and literature review
Padmanabhan Dhanasekar1, Vilvapathy Senguttuvan Karthikeyan, Nagarajan Rajkumar
1Department of Surgical Oncology, Tata Memorial Hospitals, Mumbai, India.
Background:
Cutaneous angiosarcoma is a rare tumor of the elderly male, most commonly affecting the head and neck region. It is difficult to differentiate this tumor from hemangiomas, hemangioblastomas, Kaposi sarcoma, squamous cell carcinoma and anaplastic melanomas.
Methods:
Case report and review of pertinent English medical literature.
Case Summary:
We report a case of a 60-year-old male presenting with multiple nodules over the scalp where a preoperative histopathologic diagnosis of squamous cell carcinoma was made by wedge biopsy from the tumor. Postoperative histopathology and immuno histochemistry of the wide local excision specimen proved the tumor to be cutaneous angiosarcoma and the patient completed adjuvant radiotherapy. He is now on regular follow-up for 1 year without recurrence.
Conclusions:
Cutaneous angiosarcoma must be kept in mind in view of its rarity especially in extensive involvement of the scalp by malignancy. The primary treatment is wide local excision with adequate skin cover and adjuvant chemotherapy and radiotherapy in positive margins and lymph node metastasis.
