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Temporal and geographic trends in celiac disease publications: a bibliometric analysis
David Narotsky1, Peter H R Green, Benjamin Lebwohl
1Celiac Disease Center, Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA.
Insights
Publication output for celiac disease (CD) is increasing significantly, outpacing general medical literature growth. Research on CD is becoming more widespread across journals but is increasingly concentrated among high-volume authors, with economic factors influencing national contributions.
Area of Science:
- Gastroenterology
- Medical Publication Analysis
- Bibliometrics
Background:
- Celiac disease (CD) diagnosis rates remain low despite increasing prevalence.
- Research output on CD may be underrepresented compared to other gastrointestinal conditions.
- Investigating publication trends can shed light on research focus and potential diagnostic gaps.
Purpose of the Study:
- To quantify and analyze the publication output of celiac disease research.
- To compare celiac disease publication trends with those of Crohn's disease and Helicobacter pylori.
- To assess changes in publication volume and distribution over time.
Main Methods:
- PubMed database search from 1980-2009 for celiac disease, Crohn's disease, and Helicobacter pylori publications.
- Analysis of publication diffusion across journals and authors.
- Correlation analysis between national economic indicators and publication output.
Main Results:
- Celiac disease publication numbers show a steady increase, accelerating after 1995.
- Crohn's disease publications also increased, while Helicobacter pylori publications declined.
- Celiac disease research became more dispersed across journals but concentrated among high-volume authors; national output correlated with GDP.
Conclusions:
- Celiac disease research output is growing disproportionately to the overall medical literature.
- Publication landscape for CD shows increased journal diffusion but author concentration.
- Economic factors significantly influence a nation's contribution to celiac disease literature.
Background:
Despite the increasing prevalence of celiac disease (CD), the rate of diagnosis remains low. This may be related to the lack of research and publications on CD compared with other gastrointestinal conditions. We hypothesized that CD publications are underrepresented as compared with other gastrointestinal illnesses, and are particularly underrepresented in the USA.
Goal:
To explore the rate of CD publication output, comparing it with other gastrointestinal conditions, and to assess for changes over time.
Study:
We used an iterative search process to identify all articles in PubMed from 1980 to 2009, and compared the number of publications featuring CD to Crohn's disease and Helicobacter pylori. We analyzed CD publication output with respect to its degree of diffusion among journals and authors, and assessed for an association between economic parameters and output.
Results:
The number of publications has increased steadily since 1980, with acceleration in the rate of increase beginning in 1995; this trend was also observed in the number of publications in Crohn's disease, whereas the number of publications for H. pylori has begun to decline. The 10 journals with the largest number of Crohn's disease publications were responsible for 29% of all Crohn's disease research output in 1995-1999 and 30% in 2005-2009. In contrast, the top 10 CD journals were responsible for 34% of CD output in 1995-1999, but only 25% in 2005-2009 (P<0.0001). Publication output per nation was moderately associated with gross domestic product (r=0.59, P<0.0001).
Conclusion:
The number of publications in CD is increasing, out of proportion to the overall growth of the peer-reviewed medical literature. CD publications are spread throughout a larger number of journals, but are more dominated by high-volume authors. Economic factors are associated with national contributions to the world literature in CD.
