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Updated: May 21, 2026

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
Published on: August 16, 2021
Experience with noncardiac surgery in destination therapy left ventricular assist devices patients
Geetha Bhat1, Shivani Kumar, Ashim Aggarwal
1Center for Heart Transplant and Assist Devices, Oak Lawn, IL 60453, USA. geetha.bhat@advocatehealth.com
Insights
Non-heart surgeries are generally safe for patients with continuous flow left ventricular assist devices (CF-LVAD). While most procedures had good outcomes, expect increased blood transfusions due to clotting issues.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Medical Devices
Background:
- Continuous flow left ventricular assist devices (CF-LVAD) improve survival in advanced heart failure.
- Patients with CF-LVAD increasingly require noncardiac operations post-implantation.
Purpose of the Study:
- To evaluate the safety and outcomes of noncardiac operations in destination therapy CF-LVAD patients.
Main Methods:
- Retrospective review of 36 patients with CF-LVAD who underwent 63 noncardiac operations.
- Analysis of patient demographics, operation types, and perioperative complications.
Main Results:
- Most operations (84%) were elective; 16% of critically ill patients expired after emergent procedures.
- Overall good clinical outcomes and minimal intraoperative complications were observed.
- Increased intra- and postoperative blood product transfusions were noted due to coagulopathies.
Conclusions:
- Noncardiac surgery is generally safe for destination therapy CF-LVAD patients.
- Careful management of coagulopathies is crucial for optimizing outcomes.
Abstract:
Continuous flow left ventricular assist devices (CF-LVAD) are increasing the life expectancy of patients with advanced heart failure, with these patients undergoing more noncardiac operations after implantation. The purpose of this study was to determine the safety of noncardiac operations in destination therapy CF-LVAD patients. In a retrospective study of 110 CF-LVAD patients, we reviewed 36 patients who underwent 63 noncardiac operations 315.1 ± 333.5 days after LVAD placement. Fifty-four (84%) operations were elective and 10 were emergent. The mean age of the cohort was 61.4 ± 11.4 years, with the majority (81%) being men. Most patients (n = 24, 38%) underwent total abdominal operation. Of the 36 patients in the study, 23 (63.8%) patients required one surgical procedure, and 13(36.1%) patients underwent more than one procedure. Six critically ill patients (16%) of 37 expired within 30 days after emergent operation. Our study demonstrates overall good clinical outcomes with minimal intraoperative complications in LVAD patients undergoing noncardiac surgeries, except an increased propensity for intra- and postoperative transfusion of blood products because of complex coagulopathies.
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