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Updated: May 21, 2026
10:27
Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
Flagellate dermatitis caused by shiitake mushrooms.
Lidia Marilia Poppe1, Diana Anders, Hermann Kneitz
1Universitäetsklinikum Wuerzburg, Germany. lidia.derma@googlemail.com
Anais Brasileiros De Dermatologia
|June 21, 2012
Summary
Consuming raw shiitake mushrooms can cause a distinctive skin rash, known as shiitake dermatitis. This condition, characterized by itchy red bumps, typically appears within 48 hours of ingestion.
Area of Science:
- Dermatology
- Mycology
- Toxicology
Background:
- Shiitake mushrooms (Lentinus edodes) are globally popular and recognized in traditional Asian medicine for various health benefits.
- Despite culinary and medicinal uses, raw or undercooked shiitake consumption is linked to adverse dermatological reactions.
- These reactions, termed shiitake dermatitis, manifest as specific skin lesions.
Observation:
- A case study details a 36-year-old patient experiencing typical shiitake dermatitis symptoms.
- The patient developed a characteristic rash 24 hours after consuming shiitake mushrooms.
- The rash presented as linearly arranged, pruritic, erythematous papules and plaques.
Findings:
- Shiitake dermatitis is an immune-mediated reaction to lentinan, a polysaccharide in shiitake mushrooms.
- The characteristic linear lesions are pathognomonic for this condition.
- Prompt diagnosis and management are crucial for patient recovery.
Implications:
- Highlights the importance of thoroughly cooking shiitake mushrooms to prevent adverse reactions.
- Underscores the need for clinicians to consider dietary triggers in dermatological diagnoses.
- Contributes to understanding food-induced dermatoses and their management strategies.
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