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Generalized Lichen nitidus associated with Down's syndrome: case report.

Luciane Francisca Fernandes Botelho1, João Paulo Junqueira de Magalhães, Marília Marufuji Ogawa

  • 1Federal University of São Paulo, Brazil. lucianebotelho@hotmail.com

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Lichen nitidus, a skin condition causing small papules, is rarely associated with Down syndrome. This report details the fourth known case linking these two conditions.

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Area of Science:

  • Dermatology
  • Genetics

Background:

  • Lichen nitidus is a rare skin condition of unknown cause, presenting as small, flesh-colored papules.
  • It typically affects the genitalia, limbs, trunk, and abdomen, and is usually asymptomatic or causes mild itching.
  • Generalized lichen nitidus is uncommon.

Observation:

  • This case report describes a patient with lichen nitidus.
  • The patient also has Down Syndrome.
  • This represents the fourth documented instance of this association.

Findings:

  • The study highlights a rare co-occurrence of lichen nitidus and Down Syndrome.
  • The clinical presentation of lichen nitidus in this case aligns with typical descriptions.
  • The association, though rare, warrants further investigation.

Implications:

  • This case contributes to the limited literature on lichen nitidus and Down Syndrome.
  • Understanding this association may aid in early diagnosis and management of both conditions.
  • Further research is needed to explore potential pathogenetic links.