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Congenital ptosis in monozygotic twins
K P Vestal1, S R Seiff, J M Lahey
1Department of Ophthalmology, University of California, San Francisco.
Ophthalmic Plastic and Reconstructive Surgery
|January 1, 1990
Abstract:
A case of concordance for unilateral congenital ptosis in monozygotic twins is presented. The literature on genetics and congenital ptosis is reviewed. A heritability index is calculated for congenital ptosis, based on all current twin data including the present report. A value for the heritability index of 0.75 is found, suggesting a strong hereditary influence for congenital ptosis. We conclude that twin data strongly support a transmissable genetic defect as contributing to the development of congenital ptosis.