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Updated: May 21, 2026

Investigation of the Electrophysiological and Thermographic Safety Parameters of Surgical Energy Devices During Thyroid and Parathyroid Surgery in a Porcine Model

Investigation of the Electrophysiological and Thermographic Safety Parameters of Surgical Energy Devices During Thyroid and Parathyroid Surgery in a Porcine Model

Published on: October 13, 2022

Parathyroid function after open thyroidectomy: A prospective randomized study for ligasure precise versus harmonic

Gianlorenzo Dionigi¹, Sam Van Slycke, Stefano Rausei

¹Department of Surgical Sciences, University of Insubria, Varese-Como, Italy. gianlorenzo.dionigi@uninsubria.it

|June 21, 2012

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Comparing bipolar vessel sealing and ultrasonic devices for thyroidectomy, this study found ultrasonic shears led to lower parathyroid hormone levels and prolonged calcium supplementation, indicating impaired parathyroid function.

Area of Science:

Endocrine Surgery
Surgical Technology
Thyroid Disease Management

Background:

Thyroidectomy requires effective hemostasis control.
Bipolar vessel sealing and ultrasonic devices are common energy-based options.
Postoperative parathyroid function is a critical outcome measure.

Purpose of the Study:

To compare the performance of bipolar vessel sealing (LigaSure Precise) and ultrasonic (FOCUS Shears) devices in open thyroidectomy.
To evaluate the impact of these devices on postoperative parathyroid function.
To assess operative outcomes including time, morbidity, and recovery.

Main Methods:

Prospective randomized trial of 199 patients undergoing open thyroidectomy.
Comparison of LigaSure Precise (LP) and FOCUS Shears (FS) energy-based devices.

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Monitoring of intact parathyroid hormone (iPTH) and serum calcium levels postoperatively.

Main Results:

Significantly lower early postoperative iPTH levels observed in the FOCUS Shears group (p < .001).
Increased and prolonged need for oral calcium supplementation in the FOCUS Shears group.
No significant differences reported in operative time, morbidity, incision length, pain, or hospital stay between groups.

Conclusions:

Different energy-based devices significantly impact rates of postoperative parathyroid malfunction.
The FOCUS Shears device was associated with a higher incidence of transient hypoparathyroidism compared to LigaSure Precise.
Careful consideration of energy device selection is crucial for preserving parathyroid function during thyroidectomy.