Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Anticholinesterase Agents: Poisoning and Treatment

Anticholinesterase Agents: Poisoning and Treatment

Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is slower than the...

Prevention of Further Absorption of Poison

Prevention of Further Absorption of Poison

In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...

SBAR II: Application of SBAR

SBAR II: Application of SBAR

SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...

Drug Toxicity: Allergic Reactions

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...

Pharmaceutical Poisoning: Treatment Strategies

Pharmaceutical Poisoning: Treatment Strategies

Treatment strategies for poisoning are a critical aspect of emergency medicine, focusing on preventing the absorption of toxins and enhancing their elimination. When a poisoning incident occurs, the first response is to halt exposure and decontaminate the patient, particularly through gastrointestinal (GI) methods if the poison was ingested.Gastrointestinal Decontamination Techniques:Activated charcoal is the cornerstone of GI decontamination. It works through adsorption, binding the toxin to...

Local Anesthetics: Clinical Application as Spinal Anesthesia

Local Anesthetics: Clinical Application as Spinal Anesthesia

Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Selenium poisoning from consumption of contaminated wheat: a case series from rural Maharashtra, India.

Clinical toxicology (Philadelphia, Pa.)·2025

Same author

Diagnostic Signs and Symptoms of Cyanocobalamin Deficiency at Rural Setting in India: Novel Method of Supplementation.

The Journal of the Association of Physicians of India·2024

Same author

Dermatological Conundrum: Puzzling Pigmentation in Vitamin B<sub>12</sub> Deficiency and Addison's Disease.

The Journal of the Association of Physicians of India·2024

Same author

The complexities of mental health in rural India.

Lancet (London, England)·2024

Same author

A four-decade association with The Lancet.

Lancet (London, England)·2023

Same author

Imparting knowledge is no more considered a paramount contribution.

Indian journal of medical ethics·2022

Search research articles

Related Experiment Video

Updated: May 21, 2026

Captive Maintenance and Venom Extraction of Tityus serrulatus (Brazilian Yellow Scorpion) for Antivenom Production

Captive Maintenance and Venom Extraction of Tityus serrulatus (Brazilian Yellow Scorpion) for Antivenom Production

Published on: October 6, 2023

Scorpion sting: update.

Himmatrao Saluba Bawaskar¹, Pramodini Himmatrao Bawaskar

¹Bawaskar Hospital and Research Centre, Mahad, Raigad, Maharashtra, India.

The Journal of the Association of Physicians of India

|June 22, 2012

Summary

Scorpion stings cause serious health issues, including heart and breathing problems. Modern treatments like antivenom significantly reduce fatalities from severe scorpion envenomation.

Area of Science:

Toxicology
Public Health
Cardiology

Background:

Scorpion envenomation is a significant public health concern in tropical and subtropical regions.
It can lead to severe cardiotoxicity, neurotoxicity, and respiratory dysfunction.
While numerous scorpion species exist, only about 30 are medically significant, often causing similar cardiovascular effects.

Purpose of the Study:

To review the pathophysiology of scorpion envenomation.
To discuss current therapeutic strategies and their impact on clinical outcomes.
To highlight the challenges in managing scorpion stings, particularly in resource-limited settings.

Main Methods:

Review of clinical observations and case studies.
Analysis of pathophysiological mechanisms including neurotransmitter and hemodynamic studies.

More Related Videos

Electrophysiology of Scorpion Peg Sensilla

Electrophysiology of Scorpion Peg Sensilla

Published on: April 13, 2011

Harvesting Venom Toxins from Assassin Bugs and Other Heteropteran Insects

Harvesting Venom Toxins from Assassin Bugs and Other Heteropteran Insects

Published on: April 21, 2018

Related Experiment Videos

Last Updated: May 21, 2026

Captive Maintenance and Venom Extraction of Tityus serrulatus (Brazilian Yellow Scorpion) for Antivenom Production

Captive Maintenance and Venom Extraction of Tityus serrulatus (Brazilian Yellow Scorpion) for Antivenom Production

Published on: October 6, 2023

Electrophysiology of Scorpion Peg Sensilla

Electrophysiology of Scorpion Peg Sensilla

Published on: April 13, 2011

Harvesting Venom Toxins from Assassin Bugs and Other Heteropteran Insects

Harvesting Venom Toxins from Assassin Bugs and Other Heteropteran Insects

Published on: April 21, 2018

Evaluation of treatment regimens such as scorpion antivenom, vasodilators, and intensive care.

Main Results:

Scorpion envenomation presents with diverse clinical effects, primarily cardiovascular.
Advances in understanding pathophysiology and treatment have improved outcomes.
Fatality rates are significantly reduced with antivenom, vasodilators, dobutamine, and intensive care.

Conclusions:

Despite therapeutic advances, high mortality persists in rural areas due to limited access to medical facilities.
Awareness of modern treatment protocols is crucial for healthcare providers in developing countries.
Effective management of severe scorpion stings relies on timely administration of antivenom and supportive intensive care.