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[Vitamin D and cardiovascular risk]

Otto Mayer1

  • 1II. interní klinika Lékarské fakulty UK a FN Plzen. mayero@fnplzen.cz

Vnitrni Lekarstvi
|June 22, 2012
PubMed

Insights

Low vitamin D levels are linked to increased cardiovascular disease risk, highlighting its importance beyond conventional factors. This review explores the evidence and potential benefits of vitamin D supplementation for heart health.

Area of Science:

  • Cardiology
  • Endocrinology
  • Nutritional Science

Context:

  • Cardiovascular disease (CVD) pathogenesis is multifactorial, with conventional risk factors explaining only ~80% of risk.
  • Emerging evidence suggests a significant role for vitamin D in cardiovascular health.
  • Low vitamin D status is increasingly associated with heightened CVD risk.

Purpose:

  • To review current epidemiological data linking low vitamin D to cardiovascular diseases.
  • To elucidate potential pathophysiological mechanisms.
  • To summarize findings on vitamin D supplementation efficacy.

Summary:

  • Epidemiological studies consistently associate low vitamin D levels with increased cardiovascular risk.
  • Vitamin D influences cardiovascular function through various mechanisms, including effects on blood pressure and inflammation.
  • Supplementation studies provide insights into potential therapeutic benefits, though further research is ongoing.

Impact:

  • Highlights vitamin D as a potentially modifiable risk factor for cardiovascular disease.
  • Informs clinical practice regarding vitamin D assessment and supplementation in cardiovascular patients.
  • Suggests avenues for future research into vitamin D's role in cardiovascular pathophysiology and treatment.

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