Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
Vitamins01:30

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The prevalence of increased lipoprotein (a) in the Czech general population and in patients with coronary heart disease.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia·2026
Same author

Sustained Expression of Plasminogen Activator Inhibitor-1 in Patients Recovered from COVID-19 Disease.

Medical principles and practice : international journal of the Kuwait University, Health Science Centre·2025
Same author

The long-term impact of increased red blood cell distribution width detected during hospitalization for heart failure.

Biomarkers in medicine·2024
Same author

The Prognostic Impact of Renal Function Decline during Hospitalization for Heart Failure.

Kidney & blood pressure research·2023
Same author

Early vascular damage in retinal microcirculation in arterial hypertension: the Czech post-MONICA study.

Journal of hypertension·2023
Same author

Longitudinal Trends in Severe Dyslipidemia in the Czech Population: The Czech MONICA and Czech Post-MONICA Study.

Journal of cardiovascular development and disease·2023

Related Experiment Video

Updated: May 21, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

[Vitamin D and cardiovascular risk].

Otto Mayer1

  • 1II. interní klinika Lékarské fakulty UK a FN Plzen. mayero@fnplzen.cz

Vnitrni Lekarstvi
|June 22, 2012
PubMed
Summary

Low vitamin D levels are linked to increased cardiovascular disease risk, highlighting its importance beyond conventional factors. This review explores the evidence and potential benefits of vitamin D supplementation for heart health.

Area of Science:

  • Cardiology
  • Endocrinology
  • Nutritional Science

Context:

  • Cardiovascular disease (CVD) pathogenesis is multifactorial, with conventional risk factors explaining only ~80% of risk.
  • Emerging evidence suggests a significant role for vitamin D in cardiovascular health.
  • Low vitamin D status is increasingly associated with heightened CVD risk.

Purpose:

  • To review current epidemiological data linking low vitamin D to cardiovascular diseases.
  • To elucidate potential pathophysiological mechanisms.
  • To summarize findings on vitamin D supplementation efficacy.

Summary:

  • Epidemiological studies consistently associate low vitamin D levels with increased cardiovascular risk.
  • Vitamin D influences cardiovascular function through various mechanisms, including effects on blood pressure and inflammation.

More Related Videos

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
11:30

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro

Published on: June 2, 2022

Related Experiment Videos

Last Updated: May 21, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
11:30

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro

Published on: June 2, 2022

  • Supplementation studies provide insights into potential therapeutic benefits, though further research is ongoing.

    • Impact:

    • Highlights vitamin D as a potentially modifiable risk factor for cardiovascular disease.
    • Informs clinical practice regarding vitamin D assessment and supplementation in cardiovascular patients.
    • Suggests avenues for future research into vitamin D's role in cardiovascular pathophysiology and treatment.