Related Experiment Video
Updated: May 21, 2026

Sucrose Preference and Novelty-Induced Hypophagia Tests in Rats using an Automated Food Intake Monitoring System
Published on: May 8, 2020
Polydextrose: its impact on short-term food intake and subjective feelings of satiety in males-a randomized
Viren Ranawana1, Adelaide Muller, C Jeya K Henry
1Functional Food Centre, Oxford Brookes University, Gipsy Lane, Headington, Oxford, OX3 0BP, UK. viren_ranawana@sics.a-star.edu.sg
Purpose:
Polydextrose is a low-calorie highly branched-chain glucose polymer that is poorly digested in the upper gastrointestinal tract and therefore demonstrates fibre-like properties. Fibre has been shown to increase satiety and possibly reduce food intake. Therefore, the objective of the current study was to examine the effects of polydextrose on short-term satiety and energy intake.
Methods:
In a repeated-measures randomized blind cross-over design, 26 healthy males consumed a 400-g fruit smoothie containing 12 g (3 %) of polydextrose, and a buffet lunch 60 min after the smoothie. Motivational ratings for satiety and palatability and lunch energy intake were measured. The effects of the polydextrose-containing smoothie were compared against a polydextrose-free control smoothie.
Results:
Polydextrose did not significantly alter the taste and palatability of the fruit smoothie. Consuming the polydextrose-containing smoothie resulted in a significantly lower energy intake at lunch (102 kcal less) compared to the control.
Conclusion:
Polydextrose may be a good fortificant for reducing short-term food intake.
Related Concept Videos
Glucagon-like Receptor Agonists
GLP-1, when administered in high doses intravenously, triggers insulin secretion, inhibits glucagon release, slows gastric emptying, reduces food intake, and restores normal insulin secretion. However, its rapid inactivation by the...
Bioavailability Study Design: Healthy Subjects Versus Patients
Modified-Release Drug Delivery Systems: Bioavailability
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Bioavailability Study Design: Single Versus Multiple Dose Studies
Regulation of Food Intake

