N-(Quinolin-8-yl)quinoline-2-carbox-amide.

Area of Science:

• Crystallography
• Organic Chemistry
• Supramolecular Chemistry

Background:

• Understanding molecular conformation and intermolecular interactions is crucial in crystal engineering.
• Quinoline derivatives are important scaffolds in medicinal chemistry and materials science.

Purpose of the Study:

• To elucidate the crystal structure and intermolecular interactions of the title compound, C(19)H(13)N(3)O.
• To analyze the molecular conformation and hydrogen bonding network within the crystal lattice.

Main Methods:

• Single-crystal X-ray diffraction was employed to determine the three-dimensional structure.
• Analysis of hydrogen bonding and π-π interactions was performed using crystallographic data.

Main Results:

• The dihedral angle between the two quinoline systems was determined to be 11.54(3)°.
• Intramolecular N-H⋯N (bifurcated) and C-H⋯O hydrogen bonds stabilize the molecular conformation.
• Weak intermolecular π-π interactions between quinoline rings were observed with a centroid-centroid distance of 3.7351(14) Å.

Conclusions:

• The crystal structure reveals a specific molecular conformation influenced by intramolecular hydrogen bonding.
• Intermolecular π-π interactions contribute to the overall crystal packing.