Related Experiment Video
Updated: May 21, 2026

Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions
Published on: July 28, 2022
(S)-N-Phenyl-tert-butane-sulfinamide
This study details the crystal structure of a compound containing two independent molecules. These molecules form hydrogen-bonded chains, revealing insights into molecular arrangement and absolute configuration.
Area of Science:
- Crystallography
- Chemical Physics
- Organic Chemistry
Background:
- Understanding the solid-state structure of organic compounds is crucial for predicting their physical and chemical properties.
- Hydrogen bonding plays a significant role in molecular self-assembly and crystal packing.
- Chirality is a fundamental property influencing biological activity and material science applications.
Purpose of the Study:
- To elucidate the crystal structure of the title compound, C(10)H(15)NOS.
- To investigate the intermolecular interactions governing the crystal packing.
- To determine the absolute configuration of the compound.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of intermolecular interactions, including hydrogen bonding, was performed.
- Absolute configuration was assigned based on the known chirality of a precursor molecule.
Main Results:
- The asymmetric unit contains two independent molecules with similar conformations.
- Molecules are arranged in head-to-tail hydrogen-bonded chains along the b-axis via N-H⋯O interactions.
- The absolute configuration of the compound was successfully determined.
Conclusions:
- The crystal structure of C(10)H(15)NOS reveals a specific hydrogen-bonding motif leading to chain formation.
- The determined absolute configuration provides essential stereochemical information for this chiral compound.
- This structural data contributes to the understanding of structure-property relationships in related organic molecules.
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