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Updated: May 21, 2026
09:45
Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
N-(4-Fluoro-phen-yl)-2,2-dimethyl-propan-amide
Summary
This study details the crystal structure of C(11)H(14)FNO, highlighting N-H⋯O hydrogen bonds that form molecular chains. The observed dihedral angle between the ring and amide group is 39.1 degrees.
Area of Science:
- Crystallography
- Molecular Chemistry
Background:
- Understanding crystal packing is crucial for predicting material properties.
- Hydrogen bonding significantly influences molecular arrangement in solid-state structures.
Purpose of the Study:
- To elucidate the crystal structure of the title compound C(11)H(14)FNO.
- To analyze the intermolecular interactions, specifically hydrogen bonding, within the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of hydrogen bond distances and angles was performed.
Main Results:
- The crystal structure of C(11)H(14)FNO was successfully determined.
- N-H⋯O hydrogen bonds were identified, leading to the formation of molecular chains parallel to the c axis.
- The dihedral angle between the aromatic ring and the amide group was measured at 39.1(3)°.
Conclusions:
- The crystal packing is dominated by N-H⋯O hydrogen bonds, dictating a chain-like supramolecular architecture.
- The conformational arrangement, indicated by the dihedral angle, is influenced by these intermolecular forces.
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