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Oxidation of Phenols to Quinones01:17

Oxidation of Phenols to Quinones

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Related Experiment Video

Updated: May 21, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
11:51

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Published on: February 15, 2016

2-(4-Fluoro-phen-yl)quinoxaline.

Cui-Ping Wang1, Saiyong Ma, Jiang-Long Yu

  • 1School of Chemical Engineering, University of Science and Technology Liaoning, Anshan 114051, People's Republic of China.

Acta Crystallographica. Section E, Structure Reports Online
|June 22, 2012
PubMed
Summary
This summary is machine-generated.

The crystal structure of a fluorinated quinoxaline derivative was determined. Weak intermolecular interactions were observed, indicating limited π-π stacking in the solid state.

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Last Updated: May 21, 2026

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Area of Science:

  • Crystallography
  • Organic Chemistry
  • Materials Science

Background:

  • Quinoxaline derivatives are important heterocyclic compounds with diverse applications.
  • Understanding the solid-state packing and intermolecular interactions is crucial for predicting material properties.

Purpose of the Study:

  • To elucidate the crystal structure of the title compound, 14H9FN2.
  • To investigate the intermolecular interactions, specifically π-π stacking, in the crystalline state.

Main Methods:

  • Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
  • Analysis of crystallographic data was performed to measure interatomic distances and angles.

Main Results:

  • The dihedral angle between the benzene and quinoxaline rings was found to be 22.2(3)°.
  • The minimum centroid-to-centroid separation between aromatic rings was 3.995(2) Å, suggesting weak π-π stacking.

Conclusions:

  • The crystal structure reveals a non-planar conformation of the molecule.
  • The weak intermolecular π-π interactions indicate limited electronic communication between molecules in the solid state.