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Updated: May 21, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
3-Benzyl-8-meth-oxy-2-sulfanyl-idene-1,2,3,4-tetra-hydro-quinazolin-4-one
Abstract:
The tetra-hydro-quinazole fused-ring system of the title compound, C(16)H(14)N(2)O(2)S, is roughly planar (r.m.s. deviation = 0.039 Å); the phenyl ring of the benzyl substituent is aligned at 78.1 (1)° with respect to the mean plane of the fused-ring system. In the crystal, two mol-ecules are linked by a pair of N-H⋯S hydrogen bonds about a center of inversion, generating a dimer.
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