Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Primary cerebral lymphoma--a clinico-pathological study.

C Hardwidge1, J V Diengdoh, D Husband

  • 1Mersey Regional Department of Medical and Surgical Neurology, Walton Hospital, Liverpool, England, UK.

Clinical Neuropathology
|September 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pathology-based staging for HPV-positive squamous carcinoma of the oropharynx.

Oral oncology·2016
Same author

British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders.

Journal of psychopharmacology (Oxford, England)·2010
Same author

Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy.

British journal of cancer·2009
Same author

Spina Bifida and an extra lower limb.

Acta neurochirurgica·2008
Same author

Genetic and metabolic predictors of chemosensitivity in oligodendroglial neoplasms.

British journal of cancer·2006
Same author

Setting the standard--UK neurosurgical acoustic neuroma practice.

Annals of the Royal College of Surgeons of England·2006

Primary cerebral lymphoma (PCL) survival is poor, with a median of 3 months. Radiotherapy significantly improves survival for PCL patients, offering a median of 9 months.

Area of Science:

  • Neurology
  • Oncology
  • Radiology

Background:

  • Primary cerebral lymphoma (PCL) is a rare central nervous system malignancy.
  • Understanding its clinical, radiological, and histological features is crucial for diagnosis and treatment.

Purpose of the Study:

  • To present a series of PCL patients.
  • To analyze clinical, radiological, and histological findings.
  • To evaluate treatment outcomes and survival rates.

Main Methods:

  • Retrospective review of 18 PCL patients.
  • Clinical, radiological (CT scans), and histological assessments.
  • Immunocytochemical analysis to determine lymphoma cell type.

Main Results:

Related Experiment Videos

  • Median survival was 3 months, significantly improved to 9 months with radiotherapy (p < 0.05).
  • CT scans typically showed multiple, isodense lesions with uniform contrast enhancement.
  • The series comprised 15 B-cell and 3 T-cell lymphomas.

    • Conclusions:

    • Radiotherapy offers a significant survival benefit for primary cerebral lymphoma.
    • Early diagnosis and multimodal treatment approaches are essential.
    • Further research into PCL incidence and management is warranted.