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Updated: May 21, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
[Venous air emboli in a 4 year old child]
J Neidecker1, B Blaise, J Ninet
1Service d'anesthésie-réanimation, Hospices Civils de Lyon, Hôpital Louis Pradel, 28, avenue Doyen Lépine, 69500 Bron, France. jean.neidecker@chu- lyon.fr
A pediatric surgery for nephroblastoma involving the inferior vena cava resulted in venous air embolism. Transcranial Doppler monitoring may help prevent this complication in similar complex tumor resections.
Area of Science:
- Pediatric Oncology
- Cardiovascular Surgery
- Radiology
Background:
- A 4-year-old girl presented with a nephroblastoma extending into the inferior vena cava (IVC).
- Surgical resection required cardiopulmonary bypass and a large opening in the IVC.
Observation:
- Following tumor resection, bilateral mydriasis was observed.
- A CT scan confirmed massive venous air embolism.
Findings:
- The likely cause of air embolism was retrograde entry through the large IVC opening during tumor removal.
- No other cause for the air embolism was identified.
Implications:
- This case highlights a potential risk of venous air embolism during complex IVC tumor resections in pediatric patients.
- Implementing transcranial Doppler monitoring during such procedures could aid in early detection and prevention of air embolism.
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