Related Experiment Video
Updated: May 21, 2026

Orthotopic Left Lung Transplantation in Rats
Published on: July 3, 2025
[Place of traditional CBP in bipulmonary transplantation]
H Rozé1, R Sigonney, L Barandon
1CHU de Bordeaux, Service d'anesthésie réanimation 2, F-33600 Pessac, France. hadrien.roze@chu- bordeaux.fr
Abstract:
Initially double-lung transplantation (DLT) was performed with airway anastomosis at the tracheal bifurcation requiring a cardiopulmonary bypass (CBP). Complications related to ischemia of the bronchi and trachea around the carina prompted adoption of sequential single lung implantations as the method of choice for DLT. In different studies, CPB was associated with an increase in postoperative morbidity but this was probably due to the selection of more severe patients. Moreover, important progress in the technology of CPB has occurred. Therefore, the systematic use of CPB during sequential lung transplantation might have some interest by limiting the occurrence of ventilation and perfusion injuries. This article discusses the potential beneficial effects of CPB during double-lung transplantation.

