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Coordination between RAB GTPase and phosphoinositide regulation and functions

Steve Jean1, Amy A Kiger

  • 1Section of Cell and Developmental Biology, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0380, USA. sjean@ucsd.edu

Nature Reviews. Molecular Cell Biology
|June 23, 2012
PubMed
Summary

Coordinated regulation of RAB GTPases and phosphoinositides ensures precise membrane trafficking. Their regulatory enzymes interact physically and functionally, guiding effector recruitment for accurate membrane remodelling.

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