Related Experiment Video
Updated: May 21, 2026

05:40
Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs
Published on: December 22, 2023
Congenital high airway obstruction syndrome without tracheoesophageal fistula and with in utero decrease in relative
Rieko Furukawa1, Toshinori Aihara, Yuko Tazuke
1Department of Pediatric Medical Imaging, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi, Japan, 329-0498. rieppef-tym@umin.net
Pediatric Radiology
|June 23, 2012
Summary
Congenital high airway obstruction syndrome (CHAOS) cases may show imaging improvements not always linked to fistulas. Other factors likely reduce fetal intrathoracic pressure in CHAOS.
Area of Science:
- Medical imaging
- Fetal medicine
- Pediatric surgery
Background:
- Congenital high airway obstruction syndrome (CHAOS) presents with specific US and MRI findings like airway occlusion and lung hyperinflation.
- CHAOS can lead to fetal hydrops and ascites due to increased intrathoracic pressure.
Observation:
- A case of CHAOS demonstrated sequential improvements on serial fetal MRI scans.
- These improvements suggested a decrease in fetal intrathoracic pressure.
Findings:
- Despite observed imaging improvements, no spontaneous tracheoesophageal fistula was identified.
- This challenges the assumption that fistula formation is the sole cause of pressure reduction in CHAOS.
Implications:
- Imaging improvements in CHAOS may occur without a fistula, indicating alternative mechanisms for pressure relief.
- Further research is needed to identify other factors contributing to decreased fetal intrathoracic pressure in CHAOS.
Related Concept Videos
Trachea
The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of the...
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of the...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Atelectasis II: Pathophysiology
Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...
Breathing
The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
Hiatal Hernia
A hiatal hernia is the abnormal protrusion of the stomach or other abdominal organs through the esophageal hiatus of the diaphragm into the thoracic cavity.Normally, the gastroesophageal junction (GEJ) lies below the diaphragm and is supported by the phrenoesophageal membrane, the diaphragmatic crura, and connective tissues. Weakening of these structures—due to aging, congenital defects like a short esophagus, or increased intra-abdominal pressure from coughing, obesity, pregnancy, or heavy...
Pulmonary Cycle: Exhalation
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...

