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Published on: September 14, 2018
Food allergy: temporal trends and determinants.
Moshe Ben-Shoshan1, Elizabeth Turnbull, Ann Clarke
1Division of Pediatric Allergy and Clinical Immunology, Department of Pediatrics, McGill University Health Centre, Montreal, Quebec, Canada. moshebenshoshan@gmail.com
Food allergy prevalence has increased, with peanut allergy also rising, though rates may now be stabilizing in developed nations. Genetic, environmental, and demographic factors likely contribute to its development and rise.
Area of Science:
- Allergy and Immunology
- Epidemiology
- Public Health
Background:
- Food allergy prevalence has notably increased in recent decades.
- The exact pathogenesis and contributing factors remain incompletely understood.
- Existing research indicates a rise in general food allergy and specifically peanut allergy.
Purpose of the Study:
- To assess temporal trends in food allergy prevalence.
- To identify potential genetic, environmental, and demographic determinants of food allergy.
- To explore hypotheses explaining the observed increase in food allergy rates.
Main Methods:
- A systematic literature review was conducted.
- The MEDLINE (PubMed) database was searched for studies published between January 1, 2002, and January 31, 2012.
- Studies focusing on temporal trends and contributing factors to food allergy were analyzed.
Main Results:
- Overall food allergy prevalence increased by 0.60%, and peanut allergy by 0.027%.
- Prevalence appears to have stabilized in developed countries.
- Genes, environmental exposures, and demographic characteristics are implicated in food allergy development.
Conclusions:
- The rise in food allergy prevalence is multifactorial, involving genetic and environmental interactions.
- While prevalence has increased, it may be stabilizing in certain regions.
- Further research is necessary to elucidate the precise contributions of various factors to food allergy pathogenesis.
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