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Published on: April 25, 2025
Changing patterns of gastrointestinal parasite infections in Cambodian children: 2006-2011
Catrin E Moore1, Put Chhat Hor, Sona Soeng
1Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Ratchawithi Road, Ratchathewi, Bangkok 10400, Thailand. catrin@tropmedres.ac
Insights
Gastrointestinal parasites like Giardia lamblia and hookworm were common in Cambodian children. Over five years, infections rose while effective mebendazole treatments decreased.
Area of Science:
- Infectious Diseases
- Public Health
- Pediatrics
Background:
- Gastrointestinal parasites pose a significant health burden, particularly in resource-limited settings.
- Symptomatic children in Siem Reap, Cambodia, represent a key population for studying parasitic infections.
Purpose of the Study:
- To investigate the prevalence and trends of gastrointestinal parasites in symptomatic Cambodian children.
- To identify the most common parasites and assess treatment effectiveness over time.
Main Methods:
- Analysis of 16,372 fecal samples from children between 2006 and 2011.
- Direct microscopy examination for parasite detection.
- Tracking of parasite prevalence and treatment outcomes.
Main Results:
- Parasites were detected in 19.1% of samples.
- Giardia lamblia (8.0%), hookworm (5.1%), and Strongyloides stercoralis (2.6%) were most prevalent.
- Increasing infection rates and decreasing effective mebendazole treatments were observed over the study period.
Conclusions:
- Gastrointestinal parasitic infections are a persistent issue in symptomatic Cambodian children.
- There is an urgent need to address rising infection rates and declining treatment efficacy.
Abstract:
We studied gastrointestinal parasites in symptomatic Cambodian children attending a provincial hospital in Siem Reap, Cambodia between 2006 and 2011. A total of 16 372 faecal samples were examined by direct microscopy. Parasites were detected in 3121 (19.1%) samples and most common were Giardia lamblia (8.0% of samples; 47.6% disease episodes), hookworm (5.1%; 30.3%) and Strongyloides stercoralis (2.6%; 15.6%). The proportion of infected children increased, and the number of disease episodes effectively treated with a single dose of mebendazole decreased, over the 5-year period.
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