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Updated: May 21, 2026
Multiscale Structures Aggregated by Imprinted Nanofibers for Functional Surfaces
Published on: September 11, 2018
[Construction of a multiple-scale implant surface with super-hydrophilicity]
Qiao-jie Luo1, Xiao-dong Li, Ying Huang
1The Affiliated Stomatology Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
Objective:
To construct a multiple-scale organized implant surface with super-hydrophilicity.
Methods:
The SiC paper polished titanium disc was sandblasted and treated with HF/HNO₃ and HCl/H₂SO₄, then acid-etched with H₂SO₄/H₂O₂. The physicochemical properties of the surfaces were characterized by scanning electron microscope, static state contact angle and X-ray diffraction. MC3T3-E1 cells were used to evaluate the effects of the surface on the cell adhesion, proliferation and differentiation.
Results:
The acid-etching process with a mixture of H₂SO₄/H₂O₂ superimposed the nano-scale structure on the micro-scale texture. The multiple-scale implant surface promoted its hydrophilicity and was more favorable to the responses of osteoprogenitor cells, characterized by increased DNA content, enhanced ALP activity and promoted OC production.
Conclusion:
A multiple-scale implant surface with super-hydrophilicity has been constructed in this study, which facilitates cell proliferation and adhesion.
