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Updated: May 21, 2026

An Intact Pericardium Ischemic Rodent Model
Published on: September 2, 2021
Pericardial disease--anatomy and function
C R Peebles1, J S Shambrook, S P Harden
1Department of Cardiothoracic Radiology, Southampton General Hospital, Southampton University Hospitals NHS Trust, Tremona Road, Southampton, UK. Charles.peebles@suht.swest.nhs.uk
Insights
Cardiac imaging for pericardial disease is challenging. This review explores how cardiac MRI and CT provide detailed views of the pericardium, overcoming echocardiography
Area of Science:
- Cardiovascular Imaging
- Radiology
- Cardiac Pathology
Background:
- Pericardial disease diagnosis presents imaging challenges.
- Echocardiography, while first-line, has limitations in visualizing the pericardium and extracardiac structures.
- Advancements in cardiac MRI and CT offer improved diagnostic capabilities.
Purpose of the Study:
- To review the utility of CT and MRI in diagnosing pericardial disease.
- To illustrate typical imaging findings of healthy and diseased pericardium.
- To compare the strengths and weaknesses of CT and MRI modalities.
Main Methods:
- Review of CT and MRI imaging findings in pericardial disease.
- Illustration of typical appearances across various conditions.
- Exploration of functional imaging techniques.
Main Results:
- Cardiac CT and MRI demonstrate significant advancements in pericardial imaging.
- These modalities offer comprehensive visualization of the pericardium and surrounding structures.
- Specific imaging findings for diverse pericardial conditions are presented.
Conclusions:
- Cardiac CT and MRI are crucial tools for investigating pericardial disease.
- They complement echocardiography by overcoming its limitations.
- Understanding the merits of each modality aids in optimal patient management.
Abstract:
Imaging of patients with suspected or known pericardial disease remains challenging. Echocardiography is the first-line investigation for pericardial disease but it has specific limitations in terms of its abilities to visualise the pericardium fully and to identify extracardiac pathology. Cardiac cross-sectional imaging by both MRI and CT has developed significantly and now has an important role in the investigation of pericardial disease. This article examines the appearances of both healthy and diseased pericardium using CT and MRI. The typical imaging findings across a wide range of conditions are illustrated and the roles of CT and MRI are reviewed. The relative merits and weaknesses of each modality are explored and the specific functional techniques that are available are introduced.
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