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Primary duodenal NK/T-cell lymphoma with massive bleeding: A case report
Jian-Zhong Li1, Jin Tao, Dan-Yun Ruan
1Jian-Zhong Li, Jin Tao, Yi-Dong Yang, Ya-Shi Zhan, Xing Wang, Yu Chen, Bin Wu, Department of Gastroenterology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China.
World Journal of Clinical Oncology
|June 23, 2012
Summary
This case report details a rare primary duodenal natural killer/T-cell (NK/T-cell) lymphoma in a young man. The aggressive cancer presented with abdominal pain and bleeding, highlighting the importance of endoscopy for diagnosis.
Area of Science:
- Oncology
- Gastroenterology
- Hematology
Background:
- Primary natural killer/T-cell (NK/T-cell) lymphoma is an exceptionally rare gastrointestinal malignancy.
- The duodenum is an extremely uncommon site for primary NK/T-cell lymphoma, presenting unique diagnostic challenges.
Purpose of the Study:
- To report a unique case of primary duodenal NK/T-cell lymphoma.
- To highlight the clinical presentation, diagnostic methods, and poor prognosis associated with this rare condition.
Main Methods:
- Case presentation of a 26-year-old male with abdominal pain and weight loss.
- Diagnostic workup included computed tomography (CT) scan and emergency upper gastrointestinal endoscopy with biopsy.
- Pathological evaluation confirmed the diagnosis of NK/T-cell lymphoma.
Main Results:
- The patient presented with abdominal pain, weight loss, and massive upper gastrointestinal bleeding.
- Endoscopic findings revealed an irregular, bleeding ulcer on the duodenal posterior wall.
- Histopathological examination confirmed primary duodenal NK/T-cell lymphoma.
Conclusions:
- Primary duodenal NK/T-cell lymphoma is a rare entity with a poor prognosis.
- Abdominal pain and gastrointestinal bleeding can be presenting symptoms.
- Endoscopy plays a crucial role in the diagnosis of duodenal NK/T-cell lymphoma.
