Polymeric nanoparticles of FMISO: are nano-radiopharmaceuticals better than conventional ones?

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Synthesis of 68Ga Core-doped Iron Oxide Nanoparticles for Dual Positron Emission Tomography /(T1)Magnetic Resonance Imaging
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Marta de Souza Albernaz1, Beatriz Ferreira de Carvalho Patricio, Gilberto Weissmuller

  • 1Laboratory of Nanoradiopharmaceuticals – Rio de Janeiro – Brazil.

Current Radiopharmaceuticals
|June 26, 2012
PubMed

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Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...