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Updated: May 21, 2026

Aggravation of Myocardial Ischemia upon Particulate Matter Exposure in Atherosclerosis Animal Model
Published on: December 10, 2021
Cardiovascular effects of particulate air pollution exposure: time course and underlying mechanisms
J P Langrish1, J Bosson, J Unosson
1BHF/University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK. jeremy.langrish@ed.ac.uk
Abstract:
Air pollution is now recognized as an important independent risk factor for cardiovascular morbidity and mortality and may be responsible for up to 3 million premature deaths each year worldwide. The mechanisms underlying the observed effects are poorly understood but are likely to be multifactorial. Here, we review the acute and chronic effects of air pollution exposure on the cardiovascular system and discuss how these effects may explain the observed increases in cardiovascular morbidity and mortality.
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