Travel to high altitude during pregnancy: frequently asked questions and recommendations for clinicians

The effects of altitude on pregnancy have been extensively studied in high altitude residents, but there is a lack of knowledge concerning the pregnant altitude visitor. Exposure to hypoxia results in physiologic responses which act to preserve maternal and fetal oxygenation. However, these reactions are limited and maternal/fetal complications may be observed, especially in association with exercise. Certain pre-existing conditions or risk factors of hypertension/preeclampsia and/or fetal growth restriction are contra-indications for traveling to high altitude, especially after 20 weeks. The acclimatization process has to be respected to avoid acute mountain sickness without taking drugs, and at least a few days of acclimatization are required before exercising.