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Updated: May 21, 2026

Cell-based Assay Protocol for the Prognostic Prediction of Idiopathic Scoliosis Using Cellular Dielectric Spectroscopy
Published on: October 16, 2013
A new risk classification rule for curve progression in adolescent idiopathic scoliosis
C F Lee1, Daniel Y T Fong, Kenneth M C Cheung
1School of Nursing, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Background Context:
Prognostic factors for curve progression of adolescent idiopathic scoliosis (AIS) have been reported previously. There is only one existing rule that classifies AIS patients into two groups by a curvature of 25°.
Purpose:
This study aimed to develop a more refined risk classification rule for AIS.
Study Design:
This was a retrospective cohort study.
Patient Sample:
We examined 2,308 untreated AIS patients, aged 10 years and older, who had a Risser sign of 2 and lesser and a curvature less than 30° at presentation.
Outcome Measures:
Outcome was taken as the time to progression to 30°.
Methods:
Patients' clinical parameters were analyzed by Classification and Regression Tree analysis.
Results:
The new classification rule identified four risk groups of curve progression. Patients with a curvature of 26° and more and less than 18° constituted the highest and lowest risk groups, respectively. The two intermediate groups were identified by the age (11.3 years), menarcheal status, and body height (154 cm).
Conclusions:
The risk classification rule only uses information at the first presentation and can aid physicians in deriving an efficient management.
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