Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Multimodality evoked potentials in HIV infected subjects: a longitudinal study.

C L Cazzullo¹, C Gala, A Ducati

¹Istituto di Clinica Psichiatrica, Università degli Studi di Milano.

Italian Journal of Neurological Sciences

|October 1, 1990

Summary

Multimodal evoked potentials can detect early central nervous system (CNS) involvement in asymptomatic HIV infection. These findings were confirmed in a follow-up study, highlighting the procedure's diagnostic value.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Robotic spine surgery compared with fluoroscopic-assisted surgery: advantages, disadvantages, future perspectives.

Journal of robotic surgery·2025

Same author

Perioperative analgesic effects of a modified supratemporal retrobulbar block in dogs undergoing corneal and endocular surgery.

The Journal of small animal practice·2025

Same author

Corrigendum to: "The Neurology-Stability-Epidural compression assessment: A new score to establish the need for surgery in spinal metastases" Clin. Neurol. Neurosurg. 195 (2020 Aug) 105896.

Clinical neurology and neurosurgery·2021

Same author

Multishell Diffusion MRI-Based Tractography of the Facial Nerve in Vestibular Schwannoma.

AJNR. American journal of neuroradiology·2020

Same author

Analysis of anaerobic digester mixing: comparison of long shafted paddle mixing vs gas mixing.

Water science and technology : a journal of the International Association on Water Pollution Research·2020

Same author

Sugarecane molasse and vinasse added as microbial growth substrates increase calcium carbonate content, surface stability and resistance against wind erosion of desert soils.

Journal of environmental management·2020

Area of Science:

Neuroscience
Infectious Diseases
Neurology

Background:

Human Immunodeficiency Virus (HIV) can affect the central nervous system (CNS) even in asymptomatic individuals.
Early detection of CNS involvement is crucial for managing HIV infection.

Purpose of the Study:

To investigate the utility of multimodal evoked potentials (MEPs) in identifying early CNS involvement in asymptomatic HIV-infected subjects.
To assess the stability of MEP findings over an 8-12 month interval.

Main Methods:

18 asymptomatic HIV-infected subjects underwent MEP testing.
Subjects were re-evaluated after an 8-12 month interval.
Neuropsychological assessments, including the Wechsler Adult Intelligence Scale (WAIS), were performed.

Related Experiment Videos

Main Results:

13 out of 18 subjects exhibited neuropsychological changes indicative of CNS involvement, which persisted at follow-up.
The 5 subjects with initially normal MEPs remained normal at the second examination.
The subject with the most significant MEP changes also scored pathologically on WAIS assessment.

Conclusions:

Multimodal evoked potentials are effective in identifying early, subclinical CNS involvement in HIV infection.
MEP findings in asymptomatic HIV subjects can be stable over time.
Evoked potentials serve as a valuable tool for early diagnosis of HIV-related neurological complications.