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Updated: May 21, 2026

07:19
Structural Studies of Macromolecules in Solution using Small Angle X-Ray Scattering
Published on: November 5, 2018
Light scattering: a novel approach to analyze protein 4.1R FERM domain interaction with inside-out-vesicles in
Kohei Shiba1, Wataru Nunomura, Yuichi Takakuwa
1Sysmex Corporation, Kobe, Japan. Shiba.Kouhei@sysmex.co.jp
Abstract:
In this study, we describe a novel application for light scattering, a method widely used for separation of molecules in solution based on their size. We demonstrate that light scattering analysis can monitor the change in particle size of protein 4.1R prior to and after binding to red blood cell inside-out-vesicles in solution. Light scattering constitutes therefore a novel tool to analyze protein-binding association constants.
