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Updated: May 21, 2026
05:57
The Synergistic Effect of Visible Light and Gentamycin on Pseudomona aeruginosa Microorganisms
Published on: July 2, 2013
A genetically-encoded photosensitiser demonstrates killing of bacteria by purely endogenous singlet oxygen
Rubén Ruiz-González1, John H White, Montserrat Agut
1IQS School of Engineering, Universitat Ramon Llull, Vía Augusta 390, E-08017, Barcelona, Spain.
Abstract:
TagRFP, a fluorescent protein capable of photosensitizing the production of singlet oxygen, was expressed in E. coli. Subsequent exposure to green light induced bacterial cell death in a light-dose dependent manner. It is demonstrated for the first time that intracellular singlet oxygen is sufficient to kill bacteria.
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