Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
Dosage Regimen: Fixed Dose01:01

Dosage Regimen: Fixed Dose

Fixed-dose regimens are a common approach to administer drugs to achieve and maintain desired levels of the drug in the body. In this dosing strategy, a specific amount of medication is given at regular intervals, often multiple times a day, to ensure a consistent drug concentration in the bloodstream.
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...
Determination of Multiple Dosing Parameters: Loading and Maintenance Doses01:25

Determination of Multiple Dosing Parameters: Loading and Maintenance Doses

A loading dose is an essential pharmacological strategy to rapidly achieve the target plasma drug concentration necessary for an immediate therapeutic effect. This approach is especially critical for drugs characterized by slow absorption or extended half-lives, where delaying therapeutic plasma levels could compromise treatment outcomes. By administering a loading dose, clinicians ensure a prompt onset of drug action, even for agents with complex pharmacokinetic profiles.Achieving steady-state...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...
Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessing Inpatient Rehabilitation Outcomes for Pediatric Dysphagia with the PEDI-EAT-10.

Archives of rehabilitation research and clinical translation·2026
Same author

Inner Speech Can Predict Naming Treatment Outcomes in Aphasia: A Pilot, Single-Subject Design Study.

American journal of speech-language pathology·2026
Same author

Accessible decision-making capacity evaluations for patients with aphasia: a quality improvement project to develop, implement, and evaluate an online training module for interdisciplinary healthcare providers.

Disability and rehabilitation·2026
Same author

Tongue-Yoga: Precision Visual Feedback Rehabilitation Improves Tongue Agility.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society·2026
Same author

Early Feasibility and Efficacy of a Novel Skill-Based Training Program for Poststroke Dysphagia.

Archives of rehabilitation research and clinical translation·2026
Same author

Guide to Effectively Including People With Aphasia in Research.

Archives of physical medicine and rehabilitation·2025

Related Experiment Video

Updated: May 21, 2026

Transcranial Direct Current Stimulation (tDCS) of Wernicke's and Broca's Areas in Studies of Language Learning and Word Acquisition
12:49

Transcranial Direct Current Stimulation (tDCS) of Wernicke's and Broca's Areas in Studies of Language Learning and Word Acquisition

Published on: July 13, 2019

Aphasia treatment: intensity, dose parameters, and script training.

Leora R Cherney

    International Journal of Speech-Language Pathology
    |June 27, 2012
    PubMed
    Summary

    Intensive speech-language therapy aids aphasia recovery, but "more is better" is not always true. Optimizing treatment requires considering dose, inputs, and patient actions, not just session numbers.

    Area of Science:

    • Neurology
    • Speech-Language Pathology
    • Rehabilitation Science

    Background:

    • Intensive speech-language therapy (SLT) shows promise for aphasia treatment.
    • A standardized definition of treatment intensity is lacking.
    • The effectiveness of simply increasing therapy frequency (
    • more is better") is debated.

    Purpose of the Study:

    • To review current evidence on treatment intensity in aphasia therapy.
    • To analyze studies comparing high- and low-intensity treatments for aphasia.
    • To explore the relationship between computer-based script training intensity and outcomes.

    Main Methods:

    • Literature review of aphasia treatment intensity studies.
    • Analysis of parameters defining treatment intensity (e.g., number of sessions, therapeutic inputs).

    More Related Videos

    Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia
    10:15

    Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia

    Published on: July 2, 2013

    Related Experiment Videos

    Last Updated: May 21, 2026

    Transcranial Direct Current Stimulation (tDCS) of Wernicke's and Broca's Areas in Studies of Language Learning and Word Acquisition
    12:49

    Transcranial Direct Current Stimulation (tDCS) of Wernicke's and Broca's Areas in Studies of Language Learning and Word Acquisition

    Published on: July 13, 2019

    Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia
    10:15

    Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia

    Published on: July 2, 2013

  • Examination of data linking computer-based script training intensity to patient outcomes.
  • Main Results:

    • Quantifying the dose of comprehensive aphasia treatments is complex.
    • Treatment intensity alone is insufficient; active therapeutic components are crucial.
    • Dose, therapeutic inputs, and client actions influence intervention optimization.

    Conclusions:

    • Aphasia treatment intensity requires a nuanced definition beyond session frequency.
    • Optimizing aphasia interventions necessitates understanding the "active ingredients" of therapy.
    • Considering dose, therapeutic inputs, and client engagement can improve treatment outcomes.