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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Altruism01:03

Altruism

Altruistic behaviors are “unselfish” behaviors—those that help another individual at the expense of the individual carrying out the behavior. Despite the negative consequences for the altruistic animal, these behaviors are thought to have evolved for several reasons.

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Related Experiment Video

Updated: May 21, 2026

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
09:54

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

Published on: August 15, 2022

Living donation: the global perspective.

Arthur J Matas1, Francis L Delmonico

  • 1Department of Surgery, University of Minnesota, Minneapolis, MN 55455, USA. matas001@umn.edu

Advances in Chronic Kidney Disease
|June 27, 2012
PubMed
Summary
This summary is machine-generated.

Organ transplant programs vary globally, with significant differences in living donation rates and donor criteria. Unregulated markets pose ethical risks, and the transplant community opposes them.

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Area of Science:

  • Transplantation Medicine
  • Global Health Policy

Background:

  • Only 83 of 195 countries have organ transplant programs.
  • Significant global disparities exist in organ donation, particularly living donation rates.
  • Ethical considerations, donor safety, and organ shortages are key challenges in transplantation.

Purpose of the Study:

  • To analyze global variations in organ transplant programs.
  • To examine the ethical issues and challenges in living organ donation.
  • To address the problem of organ shortages and unregulated markets.

Main Methods:

  • Comparative analysis of transplant program data across countries.
  • Review of international guidelines for donor evaluation and criteria.
  • Examination of organ shortage implications and market development.

Main Results:

  • Wide variations in living donation rates exist between and within geographic areas.
  • Inconsistent donor evaluation and acceptance criteria are prevalent internationally.
  • Organ shortages have led to the emergence of unregulated markets, lacking donor/recipient protection.

Conclusions:

  • Global organ donation practices exhibit considerable heterogeneity.
  • Standardizing donor criteria and addressing organ shortages are critical.
  • The transplant community strongly condemns unregulated organ markets.