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Updated: May 21, 2026

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
Published on: April 21, 2023
Improved antibacterial activity of cephalosporins loaded in magnetic chitosan microspheres
Carmen Mariana Chifiriuc1, Alexandru Mihai Grumezescu, Crina Saviuc
1Faculty of Biology, University of Bucharest, Romania.
Abstract:
During the present study, we have evaluated magnetic chitosan as a potential drug delivery device, by specifically determining if chitosan could elute antibiotics in an active form that would be efficacious in inhibiting Staphylococcus aureus and Escherichia coli growth. We have demonstrated that the incorporation of cephalosporins of second, third and fourth generation into magnetic chitosan microspheres can possibly lead to an improved delivery of antibiotics in active forms, probably due to the inherent properties of chitosan.
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