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Assessment of Calcium Sparks in Intact Skeletal Muscle Fibers
Published on: February 24, 2014
[Tetany secondary to deficiency rickets].
M del M Fernández Martínez1, J L Gómez Llorente, M Martín González
1Complejo Hospitalario Torrecardenas, Almería, España. marfm20@gmail.com
Nutricion Hospitalaria
|June 27, 2012
Summary
Hypocalcemia, a rare childhood illness, is increasing due to immigration. This case highlights vitamin D deficiency rickets, emphasizing the need for awareness in at-risk populations.
Area of Science:
- Pediatrics
- Endocrinology
- Nutritional Science
Background:
- Rickets incidence has declined in developed nations but is rising due to immigration.
- Etiology includes low sun exposure, poor diet, phytates, exclusive breastfeeding, and genetics.
- Immigration contributes to increased rickets cases, particularly in children.
Observation:
- A 13-year-old Pakistani immigrant presented with myoclonus, paresthesias, carpopedal spasm, and gait asymmetry.
- Laboratory results revealed hypocalcemia, vitamin D deficiency (25(OH)D), and elevated parathyroid hormone.
- Symptoms are consistent with severe nutritional rickets.
Findings:
- Treatment with calcium, vitamin D, and dietary modifications normalized clinical and laboratory findings.
- The case underscores the link between hypocalcemia, vitamin D deficiency, and rickets.
- Successful management was achieved through supplementation and dietary changes.
Implications:
- Increased migration necessitates heightened awareness of rickets in pediatric populations.
- Public health strategies should address nutritional deficiencies and sun exposure in immigrant children.
- Rickets, once declining, may re-emerge as a significant pediatric health concern globally.
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