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Related Experiment Video

Updated: May 21, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

PET: Is myocardial flow quantification a clinical reality?

Antti Saraste1, Sami Kajander, Chunlei Han

  • 1Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, 20520 Turku, Finland. antti.saraste@utu.fi

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
|June 27, 2012
PubMed
Summary

Quantitative Positron Emission Tomography (PET) offers precise measurements of myocardial blood flow (MBF) and myocardial flow reserve (MFR). This technology shows promise for routine clinical use in diagnosing coronary artery disease and assessing stenosis severity.

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Area of Science:

  • Cardiovascular Imaging
  • Nuclear Medicine
  • Medical Technology

Background:

  • Positron Emission Tomography (PET) provides quantitative measurements of myocardial blood flow (MBF) and myocardial flow reserve (MFR).
  • Growing interest exists in translating quantitative flow analysis from research to routine clinical practice due to technological advancements and improved availability.
  • Quantitative PET has the potential to enhance the accuracy of myocardial perfusion imaging.

Purpose of the Study:

  • To review recent advances and experiences in quantitative myocardial perfusion imaging using PET.
  • To discuss the challenges and issues that need to be addressed for the clinical implementation of quantitative PET analysis.

Main Methods:

  • Review of recent literature and clinical experiences.

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High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
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High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

Related Experiment Videos

Last Updated: May 21, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
11:09

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

  • Focus on quantitative Positron Emission Tomography (PET) techniques.
  • Analysis of data related to myocardial blood flow (MBF) and myocardial flow reserve (MFR) measurements.

    • Main Results:

    • Quantitative PET enables accurate assessment of absolute MBF and MFR.
    • Improved diagnostic accuracy for multivessel coronary artery disease is achievable.
    • Better definition of the extent and functional significance of coronary stenoses.

    Conclusions:

    • Quantitative PET is a valuable tool for myocardial perfusion imaging.
    • Further work is needed to overcome barriers for routine clinical adoption.
    • Quantitative PET has the potential to significantly impact the diagnosis and management of coronary artery disease.