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Updated: May 21, 2026
Rapid Detection of Fecal Antigen of Helicobacter pylori Infection Based on Double Antibody Sandwich Detection Technology
Published on: May 23, 2025
[Evaluation of the Helicobacter pylori stool antigen test]
Jing-Xia Guo1, Jun Han, Lin Chen
1Center of Clinical Laboratory, The No. 302 Hospital of The PLA, Beijing 100039, China.
Objective:
To evaluate the clinical value of an enzyme-linked immunosorbent assay by the Helicobacter pylori stool antigen (HpSA) test for the detection of H. pylori infection.
Methods:
328 patients were measured upper gastrointestinal endoscopic examination which as gold standards and HpSA test in the meantime, comparing accuracy, sensitivity, specificity and other Indicators.
Results:
In the diagnosis of Hp infection, HpSA test had no significant difference comparing with gold standards and had a P value of over 0.5. The sensitivity of HpSA test was 94.6%, while the specificity, veracity, expected positive value, and expected negative value were 96.9%, 96.3%, 89.7% and 98.4%, respectively.
Conclusion:
The H. pylori stool antigen test is a simple, non-invasive method for accurate diagnosis of H. pylori infection.
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