Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Early experience with reduced-size liver transplants.

R A Superina1, S M Strasberg, P D Greig

  • 1Department of Surgery, University of Toronto, Ontario, Canada.

Journal of Pediatric Surgery
|November 1, 1990
PubMed
Summary

Reduced-size liver transplants (RSLT) significantly decrease waitlist mortality for pediatric liver failure patients. This innovative approach offers a viable solution to donor scarcity, improving survival rates in critically ill children.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Abstracts of presentations to the Annual Meetings of the Canadian Society of Colon and Rectal Surgeons Canadian Association of General Surgeons Canadian Association of Thoracic Surgeons: Canadian Surgery Forum, London, Ont., Sept. 19 to 22, 2002.

Canadian journal of surgery. Journal canadien de chirurgie·2023
Same author

Inelastic mean-free path and mean escape depth of 10-140 eV electrons in SiO<sub>2</sub> nanoparticles determined by Si 2p photoelectron yields.

Physical chemistry chemical physics : PCCP·2023
Same author

Clinical profiles of placenta accreta spectrum: the PACCRETA population-based study.

BJOG : an international journal of obstetrics and gynaecology·2021
Same author

[Selective embolization of a ruptured splenic artery aneurysm after a cesarean section at 32 weeks of gestation].

Gynecologie, obstetrique, fertilite & senologie·2020
Same author

[Propositions for perinatal care at extremely low gestational ages - Working group on "Extremely low gestational ages" for SFMP, CNGOF, and SFN].

Gynecologie, obstetrique, fertilite & senologie·2020
Same author

Erratum: Periodontal Soft Tissue Root Coverage Procedures: Practical Applications From the AAP Regeneration Workshop (Clinical Advances in Periodontics 2015;5:2-10).

Clinical advances in periodontics·2020

Area of Science:

  • Pediatric Surgery
  • Organ Transplantation
  • Hepatology

Background:

  • Donor liver scarcity poses a significant challenge in pediatric liver transplantation.
  • High mortality rates exist for children awaiting liver transplants, particularly those with acute liver failure or low body weight.

Observation:

  • Reduced-size liver transplants (RSLT) were implemented to address donor shortages.
  • Seven RSLT procedures were performed in six children within the past year.
  • Waitlist mortality decreased significantly compared to the period before RSLT implementation.

Findings:

  • Children undergoing RSLT had a lower average weight than other transplant recipients.
  • RSLT cases involved longer cold ischemia times and greater intraoperative blood loss.

Related Experiment Videos

  • Postoperative liver function markers (AST, PT) showed no significant differences between groups.
  • Primary RSLT procedures had a high survival rate (3/4), while retransplantation with RSLT had poorer outcomes (0/2).

    • Implications:

    • RSLT effectively reduces mortality for children on liver transplant waiting lists.
    • The technique shows promise for primary liver transplant cases in pediatric patients.
    • Further research is needed to optimize RSLT for retransplantation scenarios and manage associated risks.