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Ganglioneuroma in a child with hereditary spherocytosis

Haci Ahmet Demir1, Semanur Ozdel, Ayper Kaçar

  • 1Divisions of Pediatric Oncology, Ankara Children's Hematology Oncology Training and Research Hospital, Ankara, Turkey.

The Turkish Journal of Pediatrics
|June 28, 2012
PubMed

Hereditary spherocytosis (HS) is the most frequent cause of congenital hemolytic anemia. Extramedullary hematopoiesis (EMH) mimicking a mass may develop in the lymph nodes, kidneys, pleura, mediastinum, adrenal gland, and in particular the spleen and liver. Other than EMH, B-cell lymphoma, acute lymphoblastic leukemia, and pancreatic schwannoma cases were reported in patients with HS. We present a 13-year-old female patient with HS and ganglioneuroma in the adrenal gland. This association is probably coincidental; however, with increasing cancer cases in HS and the genetic studies being made, this association will be clarified.

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