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Psychosocial functioning of children with systemic lupus erythematosus

Orawan Louthrenoo1, Jomkwan Krairojananan, Wattana Chartapisak

  • 1Department of Paediatrics, Faculty of Medicine, Chiang Mai University, Thailand. olouthre@med.cmu.ac.th

Journal of Paediatrics and Child Health
|June 28, 2012
PubMed

Insights

Children with childhood lupus (SLE) in remission showed no increased emotional or behavioral issues compared to healthy peers. Social competence was slightly lower, but overall psychosocial functioning remained stable during inactive disease.

Area of Science:

  • Pediatric Rheumatology
  • Child Psychology
  • Chronic Illness Management

Background:

  • Systemic lupus erythematosus (SLE) is a chronic, multi-system autoimmune disease impacting children and families.
  • The chronicity and treatment of childhood SLE significantly affect patients' physical and psychosocial well-being.
  • Assessing emotional and behavioral outcomes during disease remission is crucial for comprehensive care.

Purpose of the Study:

  • To evaluate emotional and behavioral problems in children diagnosed with lupus during periods of disease remission.
  • To compare psychosocial functioning between children with SLE and healthy controls.
  • To identify potential areas of concern for children with inactive childhood lupus.

Main Methods:

  • A cohort of 40 children with SLE (aged 8-15) in remission (SLE Disease Activity Index [SLEDAI] 0-1) and 40 age-matched healthy controls were studied.
  • Children self-rated emotional states using the Children's Depression Inventory (CDI) and Multidimensional Anxiety Scale for Children (MASC).
  • Parental reports on behavior were collected using the Child Behaviour Checklist.

Main Results:

  • No significant differences were observed in depression (CDI) or anxiety (MASC) scores between children with SLE and controls.
  • Internalizing, externalizing, and total behavioral scores were comparable between the SLE and control groups.
  • Children with SLE exhibited a statistically significant lower score in social competence compared to healthy peers (P=0.03).

Conclusions:

  • Despite being a multi-system disease, childhood SLE in remission does not appear to elevate the risk of significant psychosocial dysfunctions.
  • While overall emotional and behavioral problems were not increased, a subtle impact on social competence warrants attention.
  • These findings suggest that children with inactive SLE can maintain relatively stable psychosocial functioning.
Abstract

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