Enhanced stabilization of the Tobacco mosaic virus using protic ionic liquids
Nolene Byrne1, Brendan Rodoni, Fiona Constable
1Centre for Material and Fibre Innovation, Institute of Frontier Materials, Deakin University, Geelong, Vic 3217, Australia.
Physical Chemistry Chemical Physics : PCCP
|June 28, 2012
Abstract:
We report on the use of protic ionic liquids, pILs, as solvents for the solubilisation and stabilization of viruses. We show that the shelf life of the pIL stabilized tobacco mosaic virus is significantly enhanced when compared to traditional phosphate buffer. This has new opportunities for the preparation, characterization and storage of viruses and virus based technologies.
