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[Development and evaluation of individualized fluid therapy in the elderly patients with coronary heart disease

Hong Zheng1, Hai Guo, Jian-rong Ye

  • 1Department of Anesthesia, Xinjiang Medical University, Urumqi, China. xyzhenghong@yahoo.com.cn

Zhonghua Wei Chang Wai Ke Za Zhi = Chinese Journal of Gastrointestinal Surgery
|June 28, 2012
PubMed

Insights

Individualized fluid therapy for elderly patients with coronary heart disease undergoing gastrointestinal surgery improved outcomes. This approach enhanced hemodynamic parameters and accelerated gastrointestinal function recovery, reducing hospital stays.

Area of Science:

  • Cardiovascular Surgery
  • Gastrointestinal Surgery
  • Critical Care Medicine

Context:

  • Elderly patients with coronary heart disease (CHD) undergoing gastrointestinal surgery face significant perioperative risks.
  • Optimizing fluid management is crucial for maintaining hemodynamic stability and improving outcomes in this vulnerable population.

Purpose:

  • To develop and evaluate an individualized fluid therapy strategy for elderly patients with CHD undergoing gastrointestinal surgery.
  • To compare the efficacy of individualized fluid therapy versus traditional fluid therapy in terms of hemodynamic parameters, fluid balance, and clinical outcomes.

Summary:

  • A prospective study randomized 60 elderly CHD patients undergoing gastrointestinal surgery into individualized fluid therapy (target-controlled based on cardiac index, stroke volume, stroke volume variation) and control (traditional fluid therapy) groups.
  • The individualized group showed improved cardiac index, stroke volume, and reduced serum lactic acid levels. While adverse cardiac events were not statistically different, gastrointestinal function recovery and length of hospital stay were significantly improved.

Impact:

  • Individualized fluid therapy demonstrates potential in optimizing perioperative care for elderly surgical patients with CHD.
  • This strategy may lead to better postoperative recovery, reduced complications, and shorter hospitalizations, offering a valuable approach in surgical fluid management.
Abstract

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