Related Experiment Video
Updated: May 21, 2026

11:03
Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy
Published on: January 22, 2018
Risk factors for giant retinal tears
Morteza Mehdizadeh1, Mehrdad Afarid, Mohammad Shabanpour Haqiqi
1Poostchi Ophthalmology Research Center, Department of Ophthalmology, Shiraz University of Medical Sciences, Shiraz, Iran.
Journal of Ophthalmic & Vision Research
|June 28, 2012
Summary
Younger age is a significant risk factor for giant retinal tears, a serious complication of retinal detachment. This study found that advancing age correlates with a decreased incidence of this condition.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Surgical Outcomes
Background:
- Giant retinal tears (GRTs) are a severe form of retinal detachment.
- Understanding risk factors is crucial for prevention and early intervention strategies.
Purpose of the Study:
- To identify and evaluate the key risk factors associated with the development of giant retinal tears.
- To analyze the correlation between patient demographics and clinical factors with GRTs.
Main Methods:
- Retrospective analysis of medical records from 150 patients undergoing retinal detachment surgery.
- Evaluation of potential risk factors including age, sex, trauma history, lens status, and high myopia.
- Statistical correlation analysis to determine significant associations with GRTs.
Main Results:
- A total of 26 patients (17.3%) were diagnosed with giant retinal tears.
- While 66% of patients were older than 30, younger age was found to be a significant risk factor.
- Advancing age showed a significant negative correlation, with a 6% decrease in GRT incidence per year of age.
Conclusions:
- Younger age is identified as a primary and significant risk factor for developing giant retinal tears.
- The findings highlight the importance of considering age in the risk assessment for GRTs.
Related Concept Videos
Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Photoreceptors and Visual Pathways
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

