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Updated: May 21, 2026
07:16
High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
[Chemical constituents from Corydalis yanhusuo]
Ziming Lu1, Wuxing Sun, Xuhong Duan
1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Summary
This study identified 22 chemical compounds from Corydalis yanhusuo using chromatography. Four compounds were newly discovered in this plant, expanding knowledge of its chemical profile.
Area of Science:
- Phytochemistry
- Natural Product Chemistry
Background:
- Corydalis yanhusuo is a traditional medicinal herb.
- Understanding its chemical composition is crucial for pharmacological research.
Purpose of the Study:
- To identify and characterize the chemical constituents of Corydalis yanhusuo.
Main Methods:
- Compounds were isolated using column chromatography with macroporous absorption resin, silica gel, and Sephadex LH-20.
- Structures were determined through physicochemical properties and spectral data analysis.
Main Results:
- Twenty-two compounds were isolated and identified.
- These include known alkaloids like corydaline and tetrahydropalmatine, as well as adenosine and N5-acetylornithine.
Conclusions:
- Four compounds (13-methyl-columbamine, stepharanine, adenosine, and N5-acetylornithine) were reported from this plant for the first time.
- This research contributes to the phytochemical knowledge of Corydalis yanhusuo.
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