Glucose metabolism in outpatients with new-onset hypertension in Chinese Han population

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Published on: May 17, 2024

Ping Gu1, Weimin Jiang, Maowei Cheng

  • 1Department of Endocrinology, Jinling Hospital, Nanjing University School of Medicine, Nanjing, Jiangsu Province, PR China.

Clinical and Experimental Hypertension (New York, N.Y. : 1993)
|June 29, 2012
PubMed

Insights

A high prevalence of abnormal glucose metabolism, including prediabetes and diabetes, was found in Chinese adults with new-onset hypertension. Aging, male sex, and elevated triglycerides are risk factors for these glucose abnormalities.

Area of Science:

  • Endocrinology
  • Cardiovascular Medicine
  • Public Health

Background:

  • Hypertension is a major cardiovascular risk factor.
  • Glucose abnormalities, such as prediabetes and diabetes, are increasingly prevalent globally.
  • The relationship between new-onset hypertension and glucose metabolism in the Chinese Han population requires further investigation.

Purpose of the Study:

  • To determine the prevalence of abnormal glucose metabolism in Chinese Han individuals with untreated new-onset hypertension.
  • To identify risk factors associated with prediabetes or diabetes in this hypertensive cohort.

Main Methods:

  • Cross-sectional study involving 499 new-onset hypertensive patients without prior diabetes diagnosis.
  • Assessment of glucose metabolism abnormalities.
  • Logistic regression analysis to identify associated risk factors.

Main Results:

  • 57.1% of patients exhibited abnormal glucose metabolism (prediabetes or diabetes).
  • Prevalence of glucose abnormalities increased with age.
  • Male sex, older age, higher serum triglycerides, and insulin resistance were significantly associated with increased risk of prediabetes or diabetes.

Conclusions:

  • Abnormal glucose metabolism is highly prevalent in Chinese adults with new-onset hypertension.
  • Aging, male sex, hypertriglyceridemia, and insulin resistance are key risk factors.
  • Early screening for glucose abnormalities in hypertensive patients is recommended.

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